Key publications

Recent scientific studies.

The most recent publications validating the efficacy, safety and long-term durability of the Endosleeve technique. Available in international medical databases.

Am. J. of
Gastro · 2025
Endosleeve efficacy at 10 years

First analysis of ESG results with follow-up of up to 10 years: a maintained average weight loss of 15.8% of total weight, an excellent safety profile, no mortality. Confirms the durability of the technique. Jirapinyo & Thompson et al.

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Gastrointest
Endosc · 2024
ASGE–ESGE recommendations on endoscopic bariatric therapies

Joint guideline of the American (ASGE) and European (ESGE) digestive endoscopy societies, establishing ESG as the reference endoscopic bariatric therapy for adults living with obesity. Jirapinyo, Hadefi, Thompson et al.

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JAMA Netw
Open · 2024
Semaglutide versus Endosleeve for weight loss

Comparative study between semaglutide (a GLP-1 drug) and ESG: the Endosleeve offers a lasting alternative, without lifelong treatment, with an excellent efficacy/safety ratio. Haseeb, Jirapinyo, Thompson et al.

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The Lancet
2022
Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT)

A landmark prospective, multicentre, randomised study — demonstrating the efficacy and safety of ESG compared with intensive nutritional management. Abu Dayyeh et al., 2022.

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Endosc Int
Open · 2024
Combining anti-obesity drugs & endoscopic gastric remodelling

Analysis of the efficacy of combined therapy (anti-obesity drugs + ESG), with optimal timing and agents — weight loss of up to 24%. Jirapinyo, Jaroenlapnopparat, Thompson.

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Surg Endosc
2018
Endoscopic Sleeve Gastroplasty: evolution of the technique

Description of the evolution of the ESG technique, from the first human cases to the current standardised technique. Kumar, Abu Dayyeh, Lopez-Nava et al.

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Insights

Understanding the Endosleeve, in depth.

Our breakdowns of the topics that matter: durability of results, digestive safety, and endoscopic solutions after bariatric surgery.

Durability · 10-year results

Endosleeve: solid, lasting results up to 10 years

A study published in the American Journal of Gastroenterology analyses ESG results with 10-year follow-up for the first time: 15.8% maintained weight loss, an excellent safety profile, few touch-ups needed. Proof of a durable strategy against obesity.

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Digestive safety · GERD

Endosleeve and gastro-oesophageal reflux: what you need to know

Unlike the surgical sleeve, the Endosleeve preserves the stomach's anatomy and does not cause a significant increase in reflux. A particularly attractive option for patients concerned about this issue.

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Revision · After bypass

Endoscopic bypass revision (TORe): a solution for weight regain

Several years after a gastric bypass, weight regain is possible. The TORe (Transoral Outlet Reduction) endoscopically corrects the dilatation of the anastomosis, without further surgery: 8 to 15% weight loss within the year.

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Innovation · ESG vs GLP-1

Endosleeve or GLP-1 drugs: which strategy to favour?

GLP-1 drugs require lifelong weekly injections, with weight regain on discontinuation. The Endosleeve offers a unique alternative: a single, non-surgical procedure with lasting results — with efficacy that can be enhanced by a combined approach.

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